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Mortensen DS, Sapienza J, Lee BGS, Perrin-Ninkovic SM, Harris R, Shevlin G, Parnes JS, Whitefield B, Hickman M, Khambatta G, Bisonette RR, Peng S, Gamez JC, Leisten J, Narla RK, Fultz KE, Sankar S. Use of core modification in the discovery of CC214-2, an orally available, selective inhibitor of mTOR kinase. Bioorganic & Medicinal Chemistry Letters. 2013 Mar;23(6):1588–91. doi: 10.1016/j.bmcl.2013.01.110. |