abstract |
The invention relates to compounds of formula (I) and to their salts with inorganic and organic acids, to their solvates and / or hydrates, which show high affinity and high selectivity for human NK1 receptors of substance P. The invention also relates to a process for their production, to intermediates such as compounds of formula (VII) useful in their manufacture, to pharmaceutical compositions containing said products and to their use in the manufacture of medicaments for the treatment of all pathologies associated with substance P and human NK1 receptors. |