http://rdf.ncbi.nlm.nih.gov/pubchem/patent/YU-47878-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-465 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N43-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-623 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-465 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23K20-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23K1-16 |
| filingDate | 1988-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14097ca513497f5dbc8075ae5b2548db http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98c8387cb633f986b764fa199461a86c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9584a81e3613936bea87462976cdb82 |
| publicationDate | 1996-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | YU-47878-B |
| titleOfInvention | PROCEDURE FOR OBTAINING AVERMECTIN B AND THEIR DERIVATIVES |
| abstract | PROCEDURE FOR OBTAINING AVERMECTIN AND THEIR DERIVATIVES, of the formula in which the broken line at the 22-23 position represents an optional double bond, R1 is hydroxy and is only present when the double bond is absent, R2 is 4- (alpha-L-oleandrosyl) -alpha-L -oleandrosyloxy formulas: R3 is hydrogen and R is alpha-racecarbonyl, C3-C8 alkenyl, C3-C8 alkynyl, C3-C8 alkoxyalkyl or C3-C8 alkylthioalkyl, C5-C8 cycloalkylalkyl, wherein alkyl group one alpha branched C2-C5 alkyl group, C3-C8 cycloalkyl or C5-C8 cycloalkenyl group, each of which may be optionally substituted by a methylene group or one or more C1-C4 alkyl groups or halogen atoms, or 3- or a 6-membered heterocyclic ring containing oxygen or sulfur, which may be saturated or fully or partially unsaturated and which may be optionally substituted by one or more C1-C4 alkyl group or halogen atom, comprising the aerobic fermentation of the Streptomyces avermitilis strain avermitilis strain 53692, missing dehydrogenase activity for 2-oxo acid with a gaseous string and avermectin BO-methyltransferase activity, on an aqueous medium containing an assimilating nitrogen source up to 5g (dm3 such as yeast, carbon in the amount of about 20-80g / dm3 being starch and inorganic salts in an amount of from about 0.001 to about 7g / dm3 such as salts of Ca, Mg, Na, Fe, K or Zn and a compound capable of being converted into avermectin B biosynthesis of the formula: B-COOH or a compound that can be converted to said a compound during the fermentation process of formula R- (CH2) n-2 where R is as defined above, n is 0, 2, 4 or 6 and Z is -CH2OH, -CHO, -COOR4, CH2NH2 and CONHR5, where R4 is H or C1-C6 alkyl, R5 is hydrogen, C1-C4 alkyl, -CH (COOH) CH2COOH, -CH (COOH) (CH2) 2 COOH or -CH (COOH) (CH2) 2SCH3 at a temperature of about 24 to about 33 ° C and approximately neutral pH. The application contains 2 more dependent requests. |
| priorityDate | 1987-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.