http://rdf.ncbi.nlm.nih.gov/pubchem/patent/YU-46083-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fdd852ef3d6fddce90fca0c5514ff37b |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-32 |
| filingDate | 1987-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d1a63b9727ec4f72f0647a4b9e57448 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9708f139010969bee93075754ed9055c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94f3768c48d474143947522ff7e9ab16 |
| publicationDate | 1992-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | YU-46083-B |
| titleOfInvention | PROCEDURE FOR PREPARATION OF PURIN DERIVATIVES |
| abstract | A process for the preparation of purine derivatives of the formula I in which jR1 is hydrogen, CH3CO or higher acyl and R3 is hydrogen, CH3CO or higher acyl, PhCO, CH2Ar as benzyl or substituted benzyl, and Z OH, hydrogen or halogen, characterized in that a compound of formula II wherein R is CH 3 CO, isobutyryl or higher acyl and R 1 and R 3 have the above meaning other than hydrogen; selectively unblocking with weak bases or acids or in the presence of a catalyst into a compound of formula I in which Z = OH, R1 has the meaning of formula I and R3 has the meaning of formula I except for hydrogen which is optionally hydrogenated to a compound of formula I in which Z is halogen is obtained, which is optionally converted by hydrolysis or photochemical dehalogenation to compound I in which Z is hydrogen, or optionally compound I in which Z is OH, R1 has in formula I the meaning given and R3 also having the meaning given in formula I but not hydrogen or benzyl are blocked with a base into a compound of formula I in which R1 = R3 is hydrogen. The application contains 4 more patent claims. |
| priorityDate | 1987-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.