| abstract |
The invention relates to a drug, in particular to polypeptide compositions used for treating patients by oral administration of polypeptide drugs into their body. The proposed polypeptide composition comprises a polypeptide, molecular weights between 1000 and 21,000, as an active component, a proteolytic enzyme inhibitor, such as a soybean trypsin inhibitor, pancreatic trypsin inhibitor, aprotinin, or egg white egg whukoid, and a pharmacologically acceptable organ excipient, with the following ratio of components (in wt.%): polypeptide - 1.0-95.0; proteolytic enzyme inhibitor - 0.02-10.0; organic acid -1,0-94,0; inert excipient - residue. Materials that increase the penetration capacity of the polypeptide can be obtained into the composition to increase its effectiveness. |