http://rdf.ncbi.nlm.nih.gov/pubchem/patent/YU-16495-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c52a9bf2cda0d7f088c40f0646e913b8 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-00 |
filingDate | 1995-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b06c644196a1606315db4d9b5d7ad889 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de1d62d21b048d480780c0c7e4b3ee87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f2f42054945bae7e911a7c32667b2d5 |
publicationDate | 1998-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | YU-16495-A |
titleOfInvention | PROCEDURE FOR INSULATION AND Purification of 8-HALODERIVATES ADEHOSIN 3 ', 5'-CYCLIC PHOSPHATE |
abstract | The invention relates to the isolation of the 8-halo-derivative of cAMP from the reaction mixture, purification of the crude and obtaining the pure product in high yield in a simple, economical and safe procedure. According to the invention, the isolation of the 8-haloderivatives of cAMP is carried out in acidic aqueous medium, at a certain pH and at a certain temperature, under conditions of least solubility, which enables a high yield of the product. Purification of these compounds is carried out by conversion to an alkaline salt soluble in water and re-precipitation in water of insoluble acid form at a certain pH and temperature, yielding a product of high purity without the use of organic solvents and the HPLC method. |
priorityDate | 1995-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 18.