abstract |
A preparation in the form of a powder for application via the mucosa is described, which comprises a high molecular weight medical agent and a cationic polymer. By adding a cationic polymer (in particular, a copolymer of aminoalkyl methacrylate or polyvinyl acetal diethylaminoacetate) or by adding a cationic polymer and a viscous polymer to a high molecular weight drug, to obtain a powder formulation, effective absorption of the drug by high molecular weight can be achieved. A powdery preparation for mucosal administration which comprises a polymeric medicine and a cationic polymer. The preparation is formed by adding a cationic polymer [especially an aminoalkyl methacrylate copolymer or poly (vinyl acetal diethylaminoacetate)] to a polymeric medicine, optionally further adding a thickening polymer, and powdering the mixture. Thus, polymeric medicine can be effectively absorbed through a mucous membrane. |