Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01a96e8bbea00eeaa0b50c2a0c000dba |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-52 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-56 |
filingDate |
1999-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e08e0d65c54513aee996bd25a27021d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f627d87f7da994fbd3dc20111197ddb7 |
publicationDate |
1999-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-9965507-A1 |
titleOfInvention |
Modulating platelet function |
abstract |
Disclosed herein is a method of identifying a compound which affects the interaction between SDF-1 and platelets, comprising the steps of: (a) contacting SDF-1 with platelets in the presence of a test compound in a test sample; (b) contacting SDF-1 with platelets in the absence of a test compound in a control sample; (c) measuring the SDF-1 effect in said test and said control samples; and (d) identifying compounds which increase or decrease said SDF-1 effect in the test sample compared to the control sample. Also disclosed is a method of treating a patient with a vascular disease by administering an inhibitor of the interaction between stromal cell derived factor-1 (SDF-1) and platelets, in an amount effective to reduce the symptoms of said disease. Also disclosed is a method of stimulating the interaction between SDF-1 and platelets, as well as methods to identify compounds that modulate the above interaction. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7935692-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7662392-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1290033-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7897590-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7709486-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8153113-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005103721-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2292631-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8486416-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1411918-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2371361-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9387234-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1290033-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8663652-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7414065-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1411918-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2371361-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8242091-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3632425-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7887796-B2 |
priorityDate |
1998-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |