| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d5c4bd2e49dbb2477d6b948e24ba770f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3a65e58c1ff49d22e7ac3509270b4581
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8cf2caf35a4f97a4534d8923f7fd25a4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ab02f50207902e2db1d31bf448abdb92 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-60 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-625
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate |
1999-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a3e3767e138f1e2bdc6a04ef81a9933
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73320ce89f29a85103a15af5e4edacf5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d60f9530cb0b12be20f064cd6da24c8d |
| publicationDate |
1999-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9964449-A2 |
| titleOfInvention |
Cell-permeable peptide |
| abstract |
The present invention relates to a new method of delivery of molecules into a cell through the use of a modified signal peptide to which a peptide nucleic acid is linked. The signal peptide will comprise at least one positively charged amino acid residue, or functional equivalent thereof. The addition of such positively charged residues can serve as a linker group for the attachment of peptide nucleic acids to the signal peptide thus increasing the number of peptide nucleic acid sequences delivered by the signal peptide and therefore its functional efficiency. Extension of the signal peptide at the C or N terminus through the addition of a single or multiple charged residue or analogues thereof will modify and improve signal peptide delivery function by increasing the solubility and cell permeability characteristics of the signal peptide. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7432045-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8748566-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8748565-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1339431-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10767181-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015119340-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10072065-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10421967-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0127154-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7371809-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7316819-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1862471-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8835377-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8017727-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4896333-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02055545-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1862471-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2346616-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0157072-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0127154-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10377813-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0157072-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2819514-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9504727-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11591598-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1339431-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8088734-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2003522185-A |
| priorityDate |
1998-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |