| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bd369d72479aafb3b61e9a6e5a9b9d85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_36749e82d41180e692aad1571b93d234
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1024761e938081978f89977eaa638bde
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1598e63bbde4ed0afdd669f9f6f8897a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aa8b5e0dc7ac4b3a03bbc52d62f5953b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-56 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-56 |
| filingDate |
1999-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2caaae2e648b0dc0febb75d325998ae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_690d4235b15f7de14d84dee932baafd9 |
| publicationDate |
1999-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9964440-A1 |
| titleOfInvention |
Alpha-interferon manufacturing process using immunoadsorption and virus removal filtration |
| abstract |
The present invention concerns a method of manufacturing α-interferon product from crude interferon preparations obtained from human or animal cell culture or from transgenic animals. The method comprises contacting a solvent/detergent treated composition with at least two monoclonal mouse IgG antibodies having complementary subtype specificities in an immunoadsorption step. The α-interferon subtypes bound by the monoclonal antibodies are eluted and the eluate is purified and filtered on a virus removal filter. The method according to the invention effectively removes all types of impurities present in crude interferon products, and gives rise to a highly purified and virus-safe multicomponent interferon which contains major α-interferon subtypes. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7745147-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8357652-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8268974-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006085092-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9226951-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2460283-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006085092-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2460283-B |
| priorityDate |
1998-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |