| abstract |
The present invention relates to a (GPR1). The method provides nucleotide sequences of GPR1 genes, and amino acid sequences of their encoded proteins, as well as derivatives (e.g., fragments) and analogs thereof. In a specific embodiment, the GPR1 protein is a yeast protein. The invention further relates to fragments (and derivatives and analogs thereof) of GPR1 which comprise one or more domains of a GPR1 protein. Antibodies to GPR1, its derivatives and analogs, are additionally provided. Methods of production of the GPR1 proteins, derivatives and analogs, e.g., by recombinant means, are also provided. The invention provides for screening assays for identification of compounds that modulate GPR1 expression or activity. Therapeutic methods and pharmaceutical compositions are provided. In specific examples, isolated GPR1 genes and the sequences thereof, are provided. |