| abstract |
The invention relates to the use of 2-hydroxy-4-trifluoromethylbenzoïc acid derivatives as inhibitors of the activation of the nuclear transcription factor NF-λB. The invention also relates to the utilization of 2-hydroxy-4-trifluoromethylbenzoïc acid derivatives for the preparation of medicaments to treat or prevent of pathologies associated to the activation of NF-λB and/or the expression of genes which are dependent on or regulated by, at least partially, NF-λB in mammals, including humans. |