| abstract |
Aryl(or heteroaryl)azolylcarbinol derivatives (I), wherein R1 is a hydrogen atom or a lower alkyl group; R2 is a dialkylaminoalkyl or azaheterocyclylalkyl radical; Ar is an optionally substituted phenyl or thienyl radical; and Het is an optionally substituted aromatic nitrogenated heterocycle with 5 members which contains from 1 to 3 nitrogen atoms; they are efficient for the treatment of neurogenic inflammation in various pathologies such as diabetes, asthma, cystitis, gingivitis, migraine, dermatitis, rhinitis, psoriasis, lumbar and sciatic nerve inflammation, gastrointestinal troubles, ocular inflammation, etc. in mammals including humans. |