| abstract |
The invention relates to hydroxyindoles of formula (1), where R<1> and R<5> are -C1...12-alkyl, -C2...12-alkenyl, mono-, bi- or tricyclic carbocycles, mono-, bi- or tricyclic heterocycles, carbo- or heterocyclic spirocycles, and R<2> and R<3> can be hydrogen or -OH, whereby at least one of the two substituents must be -OH. The invention also relates to their use as phosphodiesterase 4 inhibitors and to a method for producing them. |