| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fc8e3afbfcf74ffac2aeccd8e3b0eee2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_66c1b22707b0276e3078713a6ddcba91
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a9d2a510723992a2351b2b5a39398eae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_22b2e9c6b710e74e9e8e3e58c8a66cdc |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10344 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-864
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-861 |
| filingDate |
1999-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bdf30ad5b42d2c34ebc2a8cfe2237046
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7072c462f7be99f7e171adcc6f8a5c2b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46d2758e2d5f417effc4cdde184ac795 |
| publicationDate |
1999-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9953084-A1 |
| titleOfInvention |
Preparation of recombinant adenovirus carrying a rep gene of adeno-associated virus |
| abstract |
Adenoviral particles are produced by incubating cells containing a helper adenovirus vector and a helper-dependent adenoviral vector including an Adeno-Associated Virus (AAV) rep gene, such as rep78. Cells are provided containing a helper adenovirus vector. A helper-dependent adenoviral vector including an AAV rep gene is introduced into the cells, for instance by infection with infective viral particles. The cells are incubated to produce adenoviral particles containing nucleic acid including the AAV rep gene. Advantageously, cells containing helper adenovirus vector are pre-incubated for 0.5-12 hours, preferably about 4 hours, to allow expression of viral proteins required for adenoviral genome replication before introducing the helper-dependent adenovirus vector including an AAV rep gene. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6627617-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1151123-A1 |
| priorityDate |
1998-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |