Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78587acbfc8d4c9e9ac3baa7021087d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c1a6fb8c71c61c9c8826960e72e2949 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4eced5315c360467fc2f4652593c048a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c380e06f149479e1b8cecee4733fd8c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-475 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-689 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-74 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate |
1999-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6084dabab093ca0b7f9d649c93d4795 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f258ded7e71f253ee96f5ea71440745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79f73d64914d2b6f1abca23825689668 |
publicationDate |
1999-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-9950672-A1 |
titleOfInvention |
Assay for growth differentiation factor 9 |
abstract |
The present invention relates to a method of identifying an agent which alters (inhibits, enhances) activity of GDF-9. The method involves combining cells having a receptor for GDF-9 and a gene, wherein expression of the gene is regulated by binding of GDF-9 to the receptor; GDF-9; and an agent to be assessed. The combination produced is maintained under conditions appropriate for binding of GDF-9 to the receptors on the cells. The extent to which binding of GDF-9 to the receptors on the cells occurs is then determined, wherein binding of GDF-9 to the receptor to a lesser or greater extent in the presence of the agent to be assessed than in its absence, is indicative of an agent which alters GDF-9 activity. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7790161-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8530235-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007112386-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110914686-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007009166-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113834936-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007112386-A3 |
priorityDate |
1998-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |