Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d3903feffe58bdf82676a43861063143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_10dcdffe0fb3226129d07200bab52bdd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d78bea194f2d0b396bb14b204a7a8ef2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c4cfeed7aab7c3123df744e4b81aaa92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da86d012b0160d4bd183c16697106e6b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9c1fb24403f34baf58c0c74ef7dca5b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69108fc12b940ede105638f37f06080b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57484 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6809 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6809 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
filingDate |
1999-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f33a0e6c09cf2f1419b3a16681013411 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51108e26546b00f390efebe513bcf142 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5af375f3f93f96a70987af768a3d2431 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7df2d49e63808ed3e10a565c8118910 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b450aaa7860b5f7047827800e56afbee |
publicationDate |
1999-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-9950456-A1 |
titleOfInvention |
P53-regulated genes |
abstract |
Many genes are identified as being p53-regulated which were not heretofore known to be p53-regulated. This includes both genes whose expression is induced and genes whose expression is repressed by the expression of wild-type p53. Monitoring expression of these genes is used to provide indications of p53 status in a cell. Such monitoring can also be used to screen for useful anti-cancer therapeutics, as well as for substances which are carcinogenic. Defects in p53 can be bypassed by supplying p53 induced genes to cells. Defects in p53 can also be bypassed by supplying antisense constructs to p53-repressed genes. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-10048633-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011150400-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6780594-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1297186-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1297186-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0162965-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0162965-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-10037769-A1 |
priorityDate |
1998-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |