| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b55a3a7ddb4fbb6f8f22cf633ce2b73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cb8f3eba86915d967beefc175437273a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc5907aa1ab585689b4734a25ad0a0aa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_11e3dfde4e1aff1d7cfcd17e606ce221 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-217
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-4813
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-2026
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-191
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-482 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48 |
| filingDate |
1999-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d82463a04cedb89ed48234a1cb36b38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6c690a0b718cfb0aea7a2c04ee0fb7d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b095f5ef637c7ad6945321b9263c11de |
| publicationDate |
1999-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9947152-A2 |
| titleOfInvention |
Use of dipeptidyl peptidase (dpp4) of fibroblast activating protein alpha for suppressing the malignant phenotype of cancer cells |
| abstract |
This invention provides a method of suppressing the malignant phenotype or inducing apoptosis of cancer cells in a subject, comprising introducing into the cancer cell an amount of a nucleic acid encoding a dipeptidyl peptidase IV protein or fibroblast activating protein-α, thereby suppressing the malignant phenotype of the cancer. This invention provides a method of treating a subject with cancer which comprises administering to the subject a pharmaceutical composition comprising a therapeutically effective amount of a purified dipeptidyl peptidase IV protein or fibroblast activating protein-α and a pharmaceutical acceptable carrier or diluent. This invention provides a method of inducing expression of dipeptidyl peptidase IV or fibroblast activating protein-α in cancer cells of a subject, comprising administering to the subject a pharmaceutical composition comprising a therapeutically effective amount of an agent capable of activating transcription of the dipeptidyl peptidase IV gene or fibroblast activating protein-α and a pharmaceutical acceptable carrier or diluent. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008011482-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009109927-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2244723-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2244723-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6709651-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008011482-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8846621-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005071073-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-100344325-C
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004045497-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004045497-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7960384-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03004046-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6949514-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6890904-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009109927-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1543161-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03004046-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1543161-A4 |
| priorityDate |
1998-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |