Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6dbb55fd08158df74c266c5b1ede7f5a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4cc25f92fc3f39a4f09be6657b9b313e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9bae3821f0d4e5040c0c35ad64f1e0f0 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 |
filingDate |
1999-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b97ddf03ca30ee1a0f9cbb7fddf37227 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f79673ec957adf36d086e19e80eae7a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3db3c7d4d68318849652945f01d3fd3a |
publicationDate |
1999-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-9944609-A1 |
titleOfInvention |
FUSED PIPERIDINE SUBSTITUTED ARYLSULFONAMIDES AS β3-AGONISTS |
abstract |
Fused piperidine substituted arylsulfonamides are β3 adrenergic receptor agonists with very little β1 and β2 adrenergic receptor activity and as such the compounds are capable of increasing lipolysis and energy expenditure in cells. The compounds thus have potent activity in the treatment of Type II diabetes and obesity. The compounds can also be used to lower triglyceride levels and cholesterol levels or raise high density lipoprotein levels or to decrease gut motility. In addition, the compounds can be used to reduce neurogenic inflammation or as antidepresssant agents. Compositions and methods for the use of the compounds in the treatment of diabetes and obesity and for lowering triglyceride levels and cholesterol levels or raising high density lipoprotein levels or for decreasing gut motility are also disclosed. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6825213-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10208027-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9365557-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9579306-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11464774-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10479784-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7119103-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10478430-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03039547-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10822331-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0240450-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7371759-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013526540-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9278937-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10961232-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6818651-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03106423-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9334244-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7420059-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6593341-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10813929-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013023274-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9862709-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9630956-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0240449-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6596734-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9701674-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9791456-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11110086-B2 |
priorityDate |
1998-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |