Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_319d761a9372b42a26bf24c9a69a589b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dd0e24efe4a20ee34c4ec1e03b28a8d9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_765a30a3416b71a71071d5a332c9560f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a4ffb0bcfb12ce2b896f2f6236e1fb8a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4705 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate |
1999-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19a65a23a18c61d301433d1039918a77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b223f8b3f5af030a2db90768c22f045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92ad11261fbe1500b0cb72cb4fa0c8a8 |
publicationDate |
1999-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-9943804-A1 |
titleOfInvention |
Mouse tcf-3 and tcf-4 and tumourigenesis related to wnt/wingless signalling |
abstract |
The invention relates to the field of diagnosis and treatment of cancer and two Wnt/Wingless signalling. The invention provides an isolated and/or recombinant nucleic acid or a specific fragment, homologue or derivative thereof, corresponding to a mammalian Tcf-3 or Tcf-4 gene with a nucleic acid sequence as shown in figure 9 and encoding a Tcf-3 or Tcf-4 protein, or fragment thereof, said protein comprising a β-catenin binding domain and capable of complexing with β-catenin in response to signalling through the Wnt/Wingless cascade. Furthermore, the invention provides a method for identifying a candidate drug comprising use of a cell comprising a nucleic acid provided by the invention. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7682607-B2 |
priorityDate |
1998-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |