| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_90d0e4980b2fd3c93d5e4a5bbfc42c30 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-1323
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-094
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0698
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0602
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-60 |
| filingDate |
1999-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a29ee55bdcdca941f849a0261e87b24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92e8e347e0be322f948e93e695db07ed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_589ffd48ee59361edf92a755b4bb74a8 |
| publicationDate |
1999-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9943787-A2 |
| titleOfInvention |
A living chimeric skin replacement |
| abstract |
The invention comprises skin replacements for improved wound healing. In one embodiment, the skin replacement is chimeric and comprises harvesting autologous epithelial cells from a patient and seeding them onto a biocompatible substrate containing allogeneic epithelial cells cultured in vitro. The living chimeric skin replacement may be implanted over a permanent dermal replacement previously implanted at the wound site. In another embodiment the skin replacement is a composite comprising an inner, middle and outer component, comprising (a) an inner component comprising a biocompatible dermal construct having a biodegradable or removable scaffold as a base; (b) a middle component comprising epithelial cells; and (c) an outer component comprising epithelial cells cultured in vitro on a dermal construct comprising a dermal portion having a biodegradable or removable scaffold as a base, said dermal portion being combined with a transitional covering and facing inward toward said middle component of epithelial cells. The invention further comprises methods of making and implanting the various skin replacements of the invention. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8765468-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9511096-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9849149-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009067601-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9504716-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2075330-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8263405-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9872877-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9597395-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7582725-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02086510-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2002303457-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03076604-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9486484-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02083160-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7741116-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03076604-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9463203-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-19949290-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6964869-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2302035-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9089417-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9492483-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02083160-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016054592-A1 |
| priorityDate |
1998-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |