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filingDate 1998-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2105c6ed92f109c85d4646712f0cfa66
publicationDate 1999-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-9942480-A1
titleOfInvention Analgesic peptides from venom of grammostola spatulata and use thereof
abstract The present invention provides novel methods of treating pain comprising administering to a mammal in need of such treatment an effective analgesic amount of a peptide having the amino acid sequence Tyr-Cys-Gln- Lys-Trp-Leu- Trp-Thr-Cys-Asp- Ser-Glu-Arg-Lys- Cys-Cys-Glu- Asp-Met-Val- Cys-Arg-Leu- Trp-Cys-Lys- Lys-Arg-Leu-NH2 (SEQ ID NO:1) or Tyr-Cys-Gln- Lys-Trp-Met- Trp-Thr-Cys- Asp-Glu-Glu- Arg-Lys-Cys- Cys-Glu-Gly- Leu-Val-Cys- Arg-Leu -Trp-Cys-Lys-Lys- Lys-Ile-Glu-Trp (SEQ ID NO:2). The invention further provides a purified peptide having the amino acid sequence of SEQ ID NO:1. The peptides of SEQ ID NO:1 and SEQ ID NO:2 can also be used in methods for identifying compounds having analgesia-inducing activity.
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priorityDate 1998-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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