Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba045776bcd32d32e3100da8dfce4e28 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43518 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
filingDate |
1998-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2105c6ed92f109c85d4646712f0cfa66 |
publicationDate |
1999-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-9942480-A1 |
titleOfInvention |
Analgesic peptides from venom of grammostola spatulata and use thereof |
abstract |
The present invention provides novel methods of treating pain comprising administering to a mammal in need of such treatment an effective analgesic amount of a peptide having the amino acid sequence Tyr-Cys-Gln- Lys-Trp-Leu- Trp-Thr-Cys-Asp- Ser-Glu-Arg-Lys- Cys-Cys-Glu- Asp-Met-Val- Cys-Arg-Leu- Trp-Cys-Lys- Lys-Arg-Leu-NH2 (SEQ ID NO:1) or Tyr-Cys-Gln- Lys-Trp-Met- Trp-Thr-Cys- Asp-Glu-Glu- Arg-Lys-Cys- Cys-Glu-Gly- Leu-Val-Cys- Arg-Leu -Trp-Cys-Lys-Lys- Lys-Ile-Glu-Trp (SEQ ID NO:2). The invention further provides a purified peptide having the amino acid sequence of SEQ ID NO:1. The peptides of SEQ ID NO:1 and SEQ ID NO:2 can also be used in methods for identifying compounds having analgesia-inducing activity. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2012300197-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013026105-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8664179-B2 |
priorityDate |
1998-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |