| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7d3ed5f7ce781d5b771bbb2d032202d2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_32803264ca781330b88913f541b7ebd2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_99505f5f312672820e9f78c254c00a4d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d8e9f5c12f54a1be68965b679d78c45
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b6b76233cba3c488e580fef529cf9042
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e8b28eec09f313af8f830204ba8e2b93 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70503
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5152
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2833
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0011 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
1999-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c627a229ea1909547475a0916813686
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3acf2eedb4e9b1ddff2c0ec642337bf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cf3958389be1525bb78904bb7c74a0e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8268ff8262d7718655b09734e639e865
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_edceb38df46083a8ce1a38e5a1aeb644 |
| publicationDate |
1999-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9942128-A1 |
| titleOfInvention |
Method for selecting tumours expressing hla-g, sensitive to anticancer treatment and uses |
| abstract |
The invention concerns a method for selecting tumours expressing HLA-G, sensitive to an anticancer treatment, which inhibits or prevents the HLA-G activity of said tumours and the uses thereof. Said method enable to establish either the HLA-G transcription profile of a solid tumour or the HLA-G expression profile of a solid tumour. The method for establishing the HLA-G transcription profile consists in: (i) drawing a tumoral sample; (ii) extracting the mRNA; (iii) reverse transcription (RT) of said RNA; (iv) successive or simultaneous amplification of the cDNA's obtained in (iii) in the presence of primers specific to each HLA-G isoform and analysing the resulting amplification products, by electrophoresis and/or specific hybridisation and (v) establishing said sample HLA-G transcription profile. The method for establishing the HLA-G expression profile consists in: (i) drawing a tumoral sample; (ii) optionally marking said sample cells; (iii) carrying out a lysis of the cells; (iv) contacting said cells which have been subjected to lysis with different antibodies directed against the class I HLA-G antigens, to form, optionally HLA-G isoform/antibodies complexes; and (v) establishing said sample HLA-G expression profile by detecting the complexes formed in step (iv). |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1491639-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2917229-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2730588-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0196564-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0196564-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-19952509-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10005845-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2810047-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11208487-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1491639-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021005001-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014072534-A1 |
| priorityDate |
1998-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |