| abstract |
A method and an apparatus for gene amplification which can be used for carrying out heating and cooling speedily and accordingly performing a heat cycle in a short time, and also is easy to handle, a method for preparing an immobilized DNA library suitable for use in this apparatus, and a method for comparing genes systematically. The apparatus for preparing an immobilized DNA library of the present invention comprises a reactor main body (10) having recesses parts for setting containers therein, a lid part (50) having a heating and cooling means (51) and a cooling means (52) above the reactor body, and containers (12) composed of substrates (41) with immobilized genes. In the apparatus, a signal from temperature measuring part (61) is compared by a computer control part (64) with a program chart, and a temperature control part (62) of a heating and cooling means and a temperature control part (63) of a cooling means (52) are rendered to act by the computer control part. Further, a plurality of DNA libraries are set in containers, to perform systematic comparison of genes. |