http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9939748-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9baf224a7f84a809ba33ea63af3c9a53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_612e959ff253051ab1090ab082d077fa |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1093 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0482 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-08 |
filingDate | 1999-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89f8a6940c03489c9f75e37a5e22ebdb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a6fefb1fedfc900ab67fc44a76facec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02bac293d5e58e43e1ea37686485baeb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0211c086b28b567153215243a25e63f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e95b9fd76793a953ccb425d386514fb6 |
publicationDate | 1999-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-9939748-A1 |
titleOfInvention | Targeting immunoreagents useful in therapeutic and diagnostic compositions and methods |
abstract | A targeting immunoreagent comprising a metal ion, a residue of a complexing agent and an immunoreactive group linked to said complNxing agent having structure (I), wherein each R and R1 is independently selected from hydrogen, alkyl, alkoxy, hydroxyalkyl, alkoxyalkyl, hydroxyalkyloxy, alkoxyalkyloxy, alkylthio, alkylthioalkyl, alkylthioalkyloxy, hydroxyalkylthio, hydroxyalkylthioalkyl, hydroxyalkylthioalkyloxy, N,N--dialkylamino, N-(hydroxyalkyl)-N-alkylamino, N,N--bis(hydroyalkyl)amino, N,N-dialkylaminoalkyl, N--(hydroxyalkyl)-N-alkylaminoalkyl, N-N-bis(hydroxyalkyloaminoalkyl), alkylformamido, formamidoalkyl, aryl, alkylaryl, alkoxyaryl, hydroxyalkylaryl, alkoxyalkylaryl, hydroxyalkyloxyaryl, alkoxyalkyloxyaryl, alkylthioaryl, hydroxyalkylthioaryl, hydroxyalkylthioalkylaryl, hydroxyalkylthioalkyloxyaryl, aralkyl, aralkyloxy, alkoxyaralkyl, alkoxyaralkyloxy, aryloxy, alkylarylaxy, alkoxyaryloxy, and heterocyclyl; each Q is independently selected from hydrogen, alkyl, hydroxyl, carboxyl, carboxyalkyl, hydroxyalkyl, alkylthioalkyl, sulfhydryl, thioalkyl, alkoxy, alkylthio, alkylamino, aminoalkyl, aminoalkylaminoalkyl, hydroxy-alkylaminoalkyl, hydroxylaminoalkyl, hydroxamido, formamidoalkyl, alkylformamido, aryl, including substituted aryl, aryloxy, heterocyclyl, carbonyliminodiacetic acid, methyle eiminodiacetic acid, methylenethioethylene-iminodiacetic acid, carboxyalkylthioalkyl, a residue of ethylenediaminetetraascetic acid (EDTA), a residue of diethylenetriaminepentaacetic acid (DTPA), hydrazinylidenediacetic acid, and a salt of any of the foregoing acids; each Z is independently selected from a heteroatom with a valence of two, a heteroatom with a valence of three, an alkylene group, an alkylene group bonded to a heteroatom having a valence of two, and an alkylene group bonded to a heteroatom having a valence of three; each X is independently selected from nitrogen and a residue of an alkylene group; each W is independently selected from hydrogen and a substituent that comprises a protein reactive group; each L' is independently selected from a chemical bond and an intra-ring linking group; each L is independently selected from a residue of an alkylene group and an extra-ring linking group; n is 1, 2, 3 or 4; and each p is independently 0, 1, 2, 3 or 4; provided that only one W is a protein reactive group; the L bonded to the W that is a protein reactive group contains 1, 2, or 3 carbon atoms and connects X to a heteroatom capable of participating in the chelation of a metal ion; and when X is a nitrogen and a heteroatom of Z is bonded to X, the heteroatom of Z is also nitrogen; and the immunoreactive group is an ST receptor binding moiety. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02070018-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9527887-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10814013-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2805994-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109535026-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8735360-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7582281-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7067111-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109535026-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9050378-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02087498-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0169259-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7229604-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02087498-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7261875-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7223380-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0125266-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10925977-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9617305-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011071927-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7632484-B2 |
priorityDate | 1998-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 360.