| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69ece09bafee7e0c49d1f7951a3faa2c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-65 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-62 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-62 |
| filingDate |
1998-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84bb74efbbc8e410367449257bacb689
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5528b6df6fedb7b062d57e43c604559
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_786163aa1183c9f3095b5ce67c727fa3 |
| publicationDate |
1999-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9934220-A2 |
| titleOfInvention |
Real-time monitoring of an analyte by chromatography using an on-line assay |
| abstract |
The presence of a contaminating analyte in a protein mixture may obscure detection of a protein of interest. In addition, antibody breakthrough is obscured by flow-through of contaminant proteins when loading cell culture fluid onto affinity columns. An on-line chromatographic assay described herein allows real-time measurement of contaminating analyte during purification or antibody breakthrough during loading and collection of a protein of interest in preparative chromatography. Breakthrough curves are generated allowing the user to end loading of cell culture fluid and/or to end effluent collection for maximization of efficient purification and preventing waste of cell culture fluid. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3683579-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3118620-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11155575-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017178526-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109564217-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102014010353-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7740747-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7740748-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8029743-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7927476-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017049227-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6395538-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10669307-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11353468-B2 |
| priorityDate |
1997-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |