http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9931504-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ed4efd5e76e25a6fc7d6dbb42cd317a6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5041 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5047 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5055 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56961 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5094 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 |
| filingDate | 1998-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b36b53b96cd628c4ae3265c1fe63c346 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2892d139ec0b5d20594e09e5921d7f6 |
| publicationDate | 1999-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-9931504-A1 |
| titleOfInvention | ACTIVATION OF TRANSCRIPTION FACTOR COMPLEX BY β(1-3) GLUCAN |
| abstract | A method of increasing activation of a nuclear factor kappa-B-like (NF-λB) transcription factor complex of p65 (rel-A) dimerized with p48 CCAAT enhancer-binding protein-beta (C/EBP-β) (NF-IL6α) (a p65/p48 transcription factor complex) in a cell, by administering underivatized, aqueous soluble β(1-3)-glucan, or a mimic of underivatized, aqueous soluble β(1-3)-glucan, is described. Also described are methods of altering the activity of underivatized, aqueous soluble β(1-3)-glucan on cells, by modulating the activation of the p65/p48 transcription factor complex. Methods of identifying the presence of immunomodulation or leukocyte priming, by detecting activation of the p65/p48 transcription factor complex, are also described. Assays for identifying agents which alter the activity of underivatized, aqueous soluble β(1-3)-glucan, as well as assays for identifying agents that mimic the effects of underivatized, aqueous soluble β(1-3)-glucan on a cell, are described, in addition to agents identified by the assays. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-749716-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0013019-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1332225-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10327638-B2 |
| priorityDate | 1997-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.