| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8c0982b0f02b1ed6d20a315370a3a3a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b1b7bf8146638f617b777ec4c4927917 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-16 |
| filingDate |
1998-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_869477829d8050d56f579e1658d1728a |
| publicationDate |
1999-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9929642-A1 |
| titleOfInvention |
Synthesis of cc-1065/duocarmycin analogs |
| abstract |
The dihydroindole C-ring found in CC-1065/duocarmycin analogs is formed by the 5-exo-trig radical cyclization of an aryl halide onto a tethered vinyl chloride forming with chlorine installed as a suitable leaving group for subsequent cyclopropane spirocyclization. The versatility of this approach is disclosed in the context of six CC-1065/duocarmycin analogs previously synthesized in this laboratory. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0183482-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7407951-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7429658-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8193249-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6909006-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7265105-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0116104-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7704924-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7129261-B2 |
| priorityDate |
1997-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |