http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9928341-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb934863a5ae8ac94b75df71b7c70378 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bd30bbbca4f24925a41e29e94e00f030 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a4e2c11fbf7c51e183cd22e8bc7f4524 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d8485b77d543ee5a32db78fcca398ad7 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1875 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-51 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-51 |
| filingDate | 1998-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d686a28e1c565f0d320bc69d8b3300d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0af20472de95d3adb60c81a7426e8dba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_952d9b600a3b570c541348065bce7d87 |
| publicationDate | 1999-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-9928341-A2 |
| titleOfInvention | Maintenance of smooth muscle integrity by morphogenic proteins |
| abstract | Disclosed are compositions and methods for maintaining the integrity of smooth muscle, particularly vascular smooth muscle. Vascular diseases are characterized by an excessive build-up of vascular smooth muscle cells, resulting in an occlusion of a blood vessel, and/or by loss of elasticity in the blood vessels. Causes of blood vessel occlusion include smooth muscle cell proliferation and inflammatory responses. Inhibition of the proliferation of smooth muscle cells or inflammatory responses represents an effective treatment for vascular disorders, such as atherosclerosis and restenosis. Treatment may include administration of a morphogenic protein. The protein itself may be delivered to the site of vascular occlusion or the protein may be delivered by a vector, such as an adenoviral vector containing a DNA insert encoding a morphogenic protein. Such compositions and methods may also inhibit the responses of smooth muscle cells to various traumas, such as exposure to toxic agents. All of these treatmetns operate to preserve the cell phenotype by inhibiting an increase in extracellular matrix proteins, such as collagen, or by maintaining the normal balance of extracellular matrix proteins, such as Types I and III collagen. |
| priorityDate | 1997-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 637.