http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9926947-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12a135a933620c99beab01d4ac785d25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1afb3b2e1a0c6ab9fa581a212b8aea2a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dd81a5b7cda41dad9e76af11dfba441b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-22 |
| filingDate | 1998-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed3664eced8b681ec20719f371c63fea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e85e14a4ab3c82760faf5903be061612 |
| publicationDate | 1999-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-9926947-A1 |
| titleOfInvention | Synthesis of long-wavelength absorbing photosensitizers |
| abstract | The present invention provides for novel therapeutic macrocycle compounds useful in photodynamic therapy that are based on the chlorin ring system. The macrocycle compounds have, in many cases, wavelengths of activation at about 670 nm, characteristic of chlorins, and are stabilized against oxidation by the attachment to the chlorin ring of a structure that comprises one or more exocyclic rings that contribute at least one nitrogen atom. Protonation or covalent modification of this nitrogen atom, or other covalent modification of the one or more exocyclic rings permits optimization of pharmacologically relevant properties including, for example, solubility. Representative chlorins include the pyridochlorins depicted by formulas (I), (II), (III). |
| priorityDate | 1997-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 258.