| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0edd0cb0f73d5e69692df1be60333672
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61f88efcda59d7062a4252ecf6886f58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c35e70f85df4a149df5867c8f37279bc |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-703
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 |
| filingDate |
1998-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efff4592dd86ad78651d011b58efc1de
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2057306514ff739b8665e538d217250a |
| publicationDate |
1999-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9923253-A1 |
| titleOfInvention |
Stromal cell derived factor-1 (sdf-1) and method of use for diagnostic and prognostic indicator of aids pathogenesis |
| abstract |
A nucleic acid sequence having a single nucleotide mutation in the 3' untranslated region of the mRNA transcript of the structural gene for stromal derived factor (SDF1-3'A) is provided. The mutation occured at an allele frequency of 6-26 % in various racial groups. SDF-1 is the principal ligand for CXCR4, a 7-transmembrane G-coupled receptor which, with CD4, provides an entry port for T-tropic HIV-1, a variety that frequently develops in AIDS patients just prior to CD4 T-lymphocyte depletion. Also provided in the invention is a method for determining the prognosis of a subject exposed to HIV-1 and a method for determining the susceptibility of a subject to HIV-1 infection. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6743594-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0127330-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7393634-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6759519-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6511826-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6800729-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0127330-A3 |
| priorityDate |
1997-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |