| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76ba102ea9c02b6633d64bf09c5b89a4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2799-022
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0083
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0089 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 |
| filingDate |
1998-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8acccb331a3ff1e1dfbf66ef984fcc10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e77205eb3f3e2103c11508dd93274e4d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb00e540fe6080fe6005a1c19ea8d3ca |
| publicationDate |
1999-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9923215-A9 |
| titleOfInvention |
Materials and methods for preventing cellular injury in humans and animals |
| abstract |
The subject invention concerns a novel process for treating a human or animal to prevent cellular or tissue injury when said human or animal is at risk for heme protein-related damage or injury, such as acute renal failure that is associated with cisplatin treatment of cancer patients. The process employs a novel vector which, via in vivo gene transfer, results in the overexpression of the HO-1 gene in the kidney. The subject invention also concerns polynucleotide vectors and plasmids comprising the polynucleotide sequences that encode an HO-1 enzyme. These vectors can be used for transforming kidney cells to express the HO-1 gene. |
| priorityDate |
1997-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |