http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9922015-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4f53ecf8a9ae47e22bf97b959d777116 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-004 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 |
filingDate | 1998-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c5467fddc48c81d47e9ed702295f583 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f218e4616892880aa0d4f26514a5da5 |
publicationDate | 1999-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-9922015-A1 |
titleOfInvention | Method for preparing optically active 5-hydroxy-3- (4'-hydroxyphenyl)-1, 1,3-trimethylindane |
abstract | A process for resolving racemic diesters of (R,S)(±)-5-hydroxy-3-(4'-hydroxyphenyl)-1,1,3-trimethylindane is disclosed. The process utilizes a microbial enzyme derived from Chromobacterium viscosum to catalyze the enantioselective and regioselective hydrolysis of the (S)(-)-enantiomer of the racemic mixture to its corresponding monoester at a faster rate than the (R)(+)-enantiomer. A substantially pure (S)(-)-indane monoester is thereby formed, while the (R)(+)-indane diester remains unreacted. The (S)(+)-monoester and the (R)(+)-diester can then be hydrolyzed using conventional techniques to form optically active (R)(+)- and (S)(-)-5-hydroxy-3-(4'-hydroxyphenyl)-1,1,3- trimethylindane enantiomers for use as monomers in the synthesis of chiral polymers. |
priorityDate | 1997-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 116.