| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d21cbff64022f95c237c0bd3ec8656ca |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2015-1488 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-4331
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-0071 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N15-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B10-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 |
| filingDate |
1998-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4f604c3d2d74665044c8f69e87c7aff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27f0dfa2ca13fe391a6e43460a87537f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80b6c99c3da91b04e79bf0dd593f650e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ebeb7561168e874afb81346b39639f1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_411f02db7a6961a5caf1884b8ff10223
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3dd2f6e444f38b089694c961cbb6b33 |
| publicationDate |
1999-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9920314-A1 |
| titleOfInvention |
Acetic acid as a signal enhancing contrast agent in fluorescence spectroscopy |
| abstract |
A method for using acetic acid as a signal enhancing contrast agent during fluorescence spectroscopy of normal and neoplastic tissue, particularly epithelium. In one aspect, the invention includes a method of detecting tissue abnormality in a diagnostic tissue sample in a patient, comprising the steps of obtaining a first fluorescence intensity spectrum from the diagnostic tissue sample; thereafter, applying acetic acid to the diagnostic tissue sample in sufficient concentration to alter the response of such diagnostic tissue sample to electromagnetic radiation for at least an effective period of time; during the effective period of time, obtaining a second fluorescence intensity spectrum from the diagnostic tissue sample; determining a parameter indicative of a change between the first and second fluorescence emission intensity spectra; and analyzing the deterimined parameter to determine a probability that the diagnostic tissue sample is normal or abnormal. |
| priorityDate |
1997-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |