http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9915687-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dc62792656aa2e858252e97e5ffaca79 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-645 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate | 1998-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_245d25501edf6c3801e3d8129eddfa01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62d0e813caea88db6062bd963b37dff0 |
| publicationDate | 1999-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-9915687-A1 |
| titleOfInvention | Multicomponent polynucleotide complex for high efficiency cell transfection |
| abstract | Novel multicomponent polynucleotide complexes for efficient transfection of cells are disclosed. The complexes comprise a bifunctional carrier component linked to a polynucleotide. The carrier binds to the polynucleotide and comprises one or more components which increase transfection efficiency and/or expression of the polynucleotide once internalized into a cell. In one embodiment, the carrier is cationic so that it complexes with the polynucleotide. In a preferred embodiment, the carrier comprises a cellular ligand. In other embodiments, the carrier further comprises an endosomolytic agent and/or a nuclear targeting agent. The multicomponent complexes can be used to transfect a variety of cells either in vitro, ex vivo, or in vivo in a highly efficient and specific manner. |
| priorityDate | 1997-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 103.