| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b6e74e60c315427154affb3c36a8eef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e70c4209b795d679aba9b3cb43115d3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_afe95b7f2647d5b57ae7d5afdeb7bc50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_662717c94dd93edb84c2df5ba0d5e45c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-101
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6834 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88 |
| filingDate |
1998-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a1194053c3bdb83da46273a091a2bf5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a85c7e174c719d1225b5ed803f45a2e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bae77955e014170c146aca13a6344e36 |
| publicationDate |
1999-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9907899-A1 |
| titleOfInvention |
Denaturing multi ion polynucleotide chromatography for detecting mutations |
| abstract |
The present invention is directed to improved methods for detection of mutations in DNA using Denaturing Matched Ion Polynucleotide Chromatography (DMIPC). The invention includes the following aspects: analysis of PCR amplification products to identify factors that affect PCR replication fidelity; design of PCR primers; selection of an optimal temperature for performing DMIPC; selection of the mobile phase composition for gradient elution; methods for column preparation and maintenance; and methods for preparing polynucleotide samples prior to chromatographic analysis. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1231993-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-784283-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7135289-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0195233-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0195233-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1056528-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1299166-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1231993-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0168919-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0168919-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0146687-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1299166-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02103045-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02103045-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02081678-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7225079-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0146687-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1056528-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02081678-A2 |
| priorityDate |
1997-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |