Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_167942674652d9e2024b2019de0d908f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_367e2cd549cf6638739c273a9aa5bc03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59e1d955a7b1560dc68cf7fd800e8fac http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d10cf78d8aedfa2a4a1998fbaa46a5f8 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1086 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 |
filingDate |
1998-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbc6af9498b452267b3281a3f14bddd2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6162a8281d2a8ce160ca35a205781d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a42f58c0bc46cc56096ced85f93b101 |
publicationDate |
1999-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-9905292-A1 |
titleOfInvention |
Method for gene screening with the use of nuclear receptors |
abstract |
Construction has been successfully made of a system whereby, when a ligand is formed by the expression of a protein capable of converting a ligand precursor into the ligand, the ligand thus formed is bound to a nuclear receptor to thereby induce the expression of a reporter gene located downstream of the target sequence. By examining gene libraries with the use of this system, genes encoding proteins capable of converting a ligand precursor into a ligand in practice have been successfully isolated. Application of this system with the use of the transcriptional regulation by nuclear receptors makes it possible to screen ligands binding to nuclear receptors, to examine whether or not a test compound is a ligand binding to nuclear receptors, and to screen genes encoding proteins capable of converting an inactive transcriptional regulatory factor into the active one over a wide range. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0218558-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1074627-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6274359-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0017334-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1074627-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0218558-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6184256-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0017334-A3 |
priorityDate |
1997-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |