| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28ca08ec3bf2fbe15a8d409dfa176527
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61f88efcda59d7062a4252ecf6886f58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec83cca27249a018bbe3cecd92cf0570
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cb0b08268e12afda0a362baf08645c25 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-864
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-865
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-866
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-863
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-521 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-04 |
| filingDate |
1998-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48e459b7648954efd6562304b63fd5d5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a35cd557b0137c6f3125f55ebe3d28f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_558803c8aa90a3b446e2a40808244083 |
| publicationDate |
1999-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9902670-A1 |
| titleOfInvention |
Method of attenuating pathogenic mycobacteria and strains of mycobacteria so attenuated |
| abstract |
This invention provides for novel attenuated strains of Mycobacterium tuberculosis and M. bovis. Attenuation is achieved by eliminating or by downregulating the expression of the α-crystallin heat shock protein gene ('acr gene'). The invention provides for vaccines and methods of vaccinating mammals for protection against Mycobacterium sp. that cause tuberculosis. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7288261-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006060484-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9339533-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2214702-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2214702-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0151649-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02054073-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8652481-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0190309-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02054073-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0151649-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2002237764-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20100084626-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0190309-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006060484-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101656301-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8815255-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10053687-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7105170-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7608277-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7740867-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9494586-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7494785-B1 |
| priorityDate |
1997-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |