| abstract |
The present invention concerns novel compounds of formula (I), a N-oxide form, a pharmaceutically acceptable acid addition salt or a stereochemically isomeric form thereof, wherein n is zero, 1, 2 or 3; X is N or CH; each R1 independently is halo, nitro, cyano, amino, hydroxy, C¿1-4?alkyl, C1-4alkyloxy or trifluoromethyl; R?2¿ is hydrogen; C¿3-7?alkenyl; C3-7alkynyl, aryl; C3-7cycloalkyl; optionally substituted C1-6alkyl; R?3 and R4¿ each independently are hydrogen, C¿1-6? alkyl, C3-7cycloalkyl or aryl; or R?3 and R4¿ taken together form a bivalent radical -R3-R4- of formula (a), (b), (c), (d), or (e), wherein R?5a, R5b, R5c, R5d¿ each independently are hydrogen, C¿1-6?alkyl or aryl; and aryl is optionally substituted phenyl; as antifungals; their preparation, compositions containing them and their use as a medicine. |