| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_26a078af47158acc12688c95a4d81c31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_09f1af8a993280cfc7b7b1479363bcc7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b44e248ba4afa7caea3c16f64ae90bb6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d7dfd84f9157ae12c41e319ec325338d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14adf5c968af01a047d05f1a2e5f28ff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_302dc61c853c03aa93eab38208335730
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_32d0eaccb2fe56f818dde28cc7cc4aff |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00 |
| filingDate |
1998-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fff94447e647c32481121115671c458
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f6e5f519397d585c7caf901791ab9b5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59b5a41b95946bc2d3e131bd81af85c6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53dccead7ffec41ad925f4a1141bb9ee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43d0ffc1d16d6aca9f186518ae1498e9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6ed9dd5649de10771ca8030e8d7d74a |
| publicationDate |
1998-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9858932-A1 |
| titleOfInvention |
Process for the selective preparation of z-isomers of 3-(2-substituted vinyl)cephalosporins |
| abstract |
Z-Isomers of compounds of general formula (IV): [wherein R1 is 2-(2-N-protected aminothiazol-4-yl)-2-alkoxyiminoacetyl or the like, R2 is hydrogen or the like; R3 is hydrogen, a carboxyl-protecting group or the like; and R8 is alkyl or the like] can be prepared at high selectivities and in high yields by reacting a compound of general formula (I): [wherein R?1, R2 and R3¿ are each as defined above; and R4 is aryl or the like] with a 4-substituted or -unsubstituted thiazole-5-carbaldehyde in a mixed solvent comprising a chlorinated hydrocarbon and a lower alkanol at a temperature of as low as +5 °C or below. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005118596-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-100358903-C
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006096679-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4659110-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010077115-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100852299-B1 |
| priorityDate |
1997-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |