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filingDate 1998-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1998-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-9856809-A1
titleOfInvention Physiologically active polyoxypeptin and deoxypolyoxypeptin and anticancer drugs containing the same
abstract Polyoxypeptin and deoxypolyoxypeptin represented by general formula (I): wherein R represents hydroxyl in the case of polyoxypeptin and hydrogen in the case of deoxypolyoxypeptin; which are novel substances having the activity of inducing apoptosis even on apoptosis-tolerant cells and obtained by culturing Streptomyces sp. MK498-98F12 strain. These compounds are physiologically active substances having the activity of inducing apoptosis on human hepatic cancer cells and AsPC-1 cells.
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