| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e7aa001f3235c07b0298867908d45e21 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-976
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-9121 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-047
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-64 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K4-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37 |
| filingDate |
1998-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa36b4714b0109e890819c2053b68935
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c315d05c46dd884757d257d6e95e97be
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8febe769e0461ad7a439b970c82e81d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ac6a379b7293adbb2d0b84471615586
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5856a6855a8663dc05934649e79104f |
| publicationDate |
1998-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9854577-A1 |
| titleOfInvention |
Cyclic peptide libraries and methods of use thereof to identify binding motifs |
| abstract |
Methods for determining an optimal binding motif for a binding compound are provided in which the binding compound is contacted with an oriented degenerate cyclic peptide library (ODCPL) under conditions which allow for interaction between the binding compound and the ODCPL such that a complex is formed between the binding compound and a subpopulation of library members capable of interacting with the binding compound. The subpopulation of library members capable of interacting with the binding compound is then separated from library members that are incapable of interacting with the binding compound. The subpopulation of library members capable of interacting with the binding compound is linearized to form a subpopulation of linearized library members. The amino acid sequence of the subpopulation of linearized library members is determined and an amino acid sequence motif is then determined for an interaction site of the binding compound, based upon the relative abundance of different amino acid residues at each degenerate position within the linearized library members. Oriented degenerate cyclic peptide libraries, and methods for purifying cyclic peptides from linear peptides, are also provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8022252-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8088733-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2319859-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2316846-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013014587-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017032859-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0065358-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2001236205-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0125257-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11578110-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03034071-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03034071-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7550431-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0125257-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2003522961-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7452862-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2016311300-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0116160-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3636807-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0065358-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8557765-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1125905-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0116160-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0160769-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017032855-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017032858-A3 |
| priorityDate |
1997-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |