| abstract |
A composition and method for preventing, reducing or eliminating fibrosis or adhesion formation or reformation in mammals following surgical, traumatic, organic or radiation injury to internal organs, peritoneal linings and other body spaces. The composition contains phospholipids that may be selected from the group consisting of phosphatidylglycerol, phosphatidylinositol or phosphatidylserine, phosphatidylcholine and phosphatidylethanolamine. The present invention also provides composition and methods to inhibit fibrosis, scarring and adhesion formation by both restoring natural lubrication, exhibiting natural tissue plasminogen activator properties and resistance to alpha phospholipase A2. Adhesion formation is inhibited by applying the composition to body cavities where tissue trauma has or is expected to occur. |