abstract |
Methods and compositions for conferring tick immunity and preventing or reducing the transmission of tick-borne pathogens. I. scapularis polypeptides and fragments, fusion and multimeric proteins, DNA molecules encoding them, antibodies directed against the polypeptides, fusion proteins or multimeric proteins. Vaccines comprising I. scapularis polypeptides alone or in addition to other protective polypeptides. Methods comprising the polypeptides, antibodies and vaccines. |