| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8eea82f432f0b71821062e1db86a1f93
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5618270c458852acabaa7f756371d5c6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_239b1fe8a19ef004b8c47c090a9c16d5 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C335-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C235-78 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C235-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C335-20 |
| filingDate |
1998-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95886c0c608f956d07d70190fb12e6eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39c8d9baa1372a62992631ec3eacae10 |
| publicationDate |
1998-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9846551-A1 |
| titleOfInvention |
Synthesis and use of biased arrays |
| abstract |
The invention provides methods for making a new type of library of compounds, referred to herein as a 'biased array'. The biased array is based on the premise that by preparing compounds that include (i) a common molecular core that is targeted or biased to interact with or bind to a defined class of target molecules, and (ii) one or more of a wide variety of so-called 'structural diversity elements', one obtains an array that simultaneously achieves broad diversity and a very high probability of including compounds that will bind to or otherwise interact with specific members of the defined target class, but that will not interact with molecules outside of the defined target class. The clear benefit is that the new arrays will provide compounds that can serve as superior lead compounds for the development of new pharmaceutical agents that are highly specific and unlikely to have undesired general biologic activity. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7932213-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7592451-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7919617-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7749999-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6824987-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6355641-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7897599-B2 |
| priorityDate |
1997-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |