http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9846275-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bcff13f8573db698307f919e6385d5c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fdafb7c21bec22a77fb1924c0065a939 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_22867aaa111a9f5a975a72a925fc503f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_90e8d14ea2c4a28ed81bb19fa5d38b57 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0461 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0406 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-04 |
| filingDate | 1998-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96e614f59b2966f2f89c9bd9e81a90ae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aae67010284b0be29f56c6dd8c3d44b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50af4aa177851d6252bc604effc489c1 |
| publicationDate | 1999-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-9846275-A3 |
| titleOfInvention | Blood-pool carrier for lipophilic imaging agents |
| abstract | A surface-modified lipoprotein-like oil-in-water emulsion useful as a blood-pool selective delivery vehicle for lipophilic imaging agents or lipophilic derivatives of water-soluble imaging agents. The blood-pool selective delivery vehicle remains in the blood for several hours, shows very little early hepatic sequestration, and is cleared from the blood within 24 hours. The mean diameter of the oil phase is less than 150 nm which minimizes sequestration by the reticuloendothelial system. The surface of the oil phase is modified with a polyethyl glycol-modified phospholipid to prevent normal interactions with the receptor sites of the hepatocytes. In radiographic imaging, radioactive or stable, synthetic or semi-synthetic polyhalogenated triglycerides, such as 2-oleoylglycerol-1,3-bis[7-(3-amino-2,4,6-triiodophenyl)heptanoate], or lipid soluble derivatives of traditional water-soluble contrast agents, such as aliphatic esters of iopanoic, diatrizoic, and acetrizoic acid, may be incorporated into the lipophilic core of a lipoprotein-like emulsion particle. |
| priorityDate | 1997-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.