Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aa84e6c0596c88b3ed7d443c075c483e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e7aa001f3235c07b0298867908d45e21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e2ac386b19dd5004e90cebd8cf24df5f |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate |
1998-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6da533df0edd28f82d6662d1f3b79b45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7653d093438d40f3b85040831961e4b2 |
publicationDate |
1998-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-9845438-A1 |
titleOfInvention |
Ucp3: an uncoupling protein homologue |
abstract |
The present invention relates to isolated and/or recombinant nucleic acids which encode a mammalian (e.g., human, mouse) uncoupling protein 3 (UCP3) and an alternative form of UCP3 designated UCP3-short form (UCP3sh). In addition, the present invention relates to nucleic acids which hybridize with the UCP3 nucleic acids described herein and functional portions thereof. Also encompassed by the invention are a nucleic acid construct comprising a nucleic acid which encodes a UCP3 protein and a host cell; a host cell comprising the nucleic acid construct which encodes UCP3; and a method for producing mammalian UCP3 comprising introducing into a host cell the nucleic acid construct which encodes UCP3 whereby the nucleic acid is expressed. The present invention also relates to isolated or recombinantly produced UCP3 protein and functional portions thereof. Also encompassed by the invention are a method of identifying an inhibitor (e.g., antibody) or enhancer of UCP3 expression and/or function, and the use of UCP3 inhibitors and enhancers. The present invention also relates to a method of detecting UCP3 in a sample obtained from a individual. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7390782-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-780815-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7342102-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6987178-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7510710-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6403784-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6620594-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0032624-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1027424-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0207754-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0047617-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1027424-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0078941-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7381413-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7816319-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0207754-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0124625-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2003503319-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6967245-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002533062-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0002577-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8293240-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7105718-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0068686-A1 |
priorityDate |
1997-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |