| abstract |
Grafts, cells and tissues for use in transplantation, transgenic animals, methods of cell selection and various uses of such material. Use of induced apoptosis as a selectable negative marker for specific cell and tissue ablation avoiding local inflammatory response and 'bystander effect' (e.g. in engrafted tissues and/or cells). Models for tissue-specific degenerative diseases and disorders and screening methods for compounds active against those diseases related to a cell/tissue specific depletion of static or expanding cell lines. |