| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a1b4b4b21b425a0f495ecb47c7e27385
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5e4e63e076d186e73fd32674efe5b9ac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8859c1c91fc9a4c625f9a8c07d970582 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-483 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01R33-483 |
| filingDate |
1998-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b30011361ff4ce8225ff289c35fd0013
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9012a5e3890bd22386d4770e17e87ee6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2f886ed579d3492f6802eb60aa4dd12 |
| publicationDate |
1998-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9841882-A1 |
| titleOfInvention |
Method of evaluating the efficacy of drug on brain nerve cells |
| abstract |
The present invention relates to a method to measure in vivo the effect of a drug on the function of the nerve cells of the brain of a patient suffering from a neurological disease, which comprises the steps of: a) measuring NAA signal intensity using MRS of the brain of the patient; b) subjecting the patient to a treatment with the drug to be tested and measuring NAA signal intensity using MRS of the brain of the patient; and c) comparing the spectra of steps a) and b) to determine whether the drug has an effect on the function of the nerve cells of the brain; whereby the increase in the NAA signal of step b) is indicative of a drug with a positive effect. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0052465-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0052465-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7342033-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004044602-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6872739-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NL-1021892-C2 |
| priorityDate |
1997-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |