Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8986d97f40265da8f98a7cad99cb7b39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8df3e10919e59e51f747ab519ea80a62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33168c56094caae6de7b1a144448fe54 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2810-6054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-13045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-13043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2810-855 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867 |
filingDate |
1998-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d1a2292dadf3f2d373fa0f76c47c4b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_473dfd59f89defd960ca5cbd18f1d7b5 |
publicationDate |
1998-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-9841644-A1 |
titleOfInvention |
Methods and compositions for genetically modifying primate bone marrow cells |
abstract |
A method is provided for genetically modifying primate bone marrow cells, comprising isolating bone marrow cells from a primate and, by means of cocultivation, exposing the isolated bone marrow cells to cells that produce a recombinant amphotropic retrovirus with a genome based on a retroviral vector that contains the genetic information to be introduced into the bone marrow cells. Recombinant amphotropic retrovirus-producing cells, suitable for use in this method also are provided, as genetically modified primate bone marrow cells with the capacity for regeneration in vivo. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005531322-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0073482-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7034010-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6730297-B1 |
priorityDate |
1997-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |